产品货号：
Z21851
中文名称：
NR1H3抗体
英文名称：
Anti-NR1H3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NR1H3 Antibody |
| 指标别名 | Liver X receptor alpha;LXR a;LXRA;LXRα;NR1H3;Oxysterols receptor LXR alpha;RLD 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | NR1H3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | LXR-A antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus human LXR-A.The immunogen is located within amino acids 50 - 100 of LXR-A. |
| 计算分子量 | 50kDa |
| 成分 | LXR-A Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | LXR-A Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | LXR-A belongs to the Liver X Receptor family that encodes highly homologous transcription factors.Like the highly homologous LXR-B,LXR-A forms heterodimers with the retinoic acid receptor RXRalpha,function as sensors for cellular oxysterols which when activated,increase the expression of genes that control sterol and fatty acid metabolism and homeostasis.Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses.Human and mouse tumors produce LXR ligands that inhibit CCR7 expression on maturing dendritic cells (DCs),thereby allowing tumor immunoescape.In mouse models,it was shown that ablating LXR-A signaling led to an immune-mediated strong inhibition of tumor growth,suggesting that manipulation of this pathway may be a viable anti-cancer approach. |
| Uniprot ID | Q13133 |
| 基因名全称 | Nuclear receptor subfamily 1,group H,member 3 |
| 蛋白名全称 | Nuclear receptor subfamily 1,group H,member 3 |
| 推荐稀释比 | LXR-A antibody can be used for detection of LXR-A by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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